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Target
Glucose-6-phosphate 1-dehydrogenase
Ligand
BDBM62014
Substrate
n/a
Meas. Tech.
G6DPH counterscreen for TbHK1 inhibitors - Analogues series
IC50
>25000±n/a nM
Citation
 PubChem, PC G6DPH counterscreen for TbHK1 inhibitors - Analogues series PubChem Bioassay (2010)[AID] 
Target
Name:
Glucose-6-phosphate 1-dehydrogenase
Synonyms:
G6PD_LEUME | glucose-6-phosphate dehydrogenase | zwf
Type:
Enzyme Catalytic Domain
Mol. Mass.:
54421.26
Organism:
Leuconostoc mesenteroides
Description:
gi_149631
Residue:
486
Sequence:
MVSEIKTLVTFFGGTGDLAKRKLYPSVFNLYKKGYLQKHFAIVGTARQALNDDEFKQLVRDSIKDFTDDQAQAEAFIEHFSYRAHDVTDAASYAVLKEAIEEAADKFDIDGNRIFYMSVAPRFFGTIAKYLKSEGLLADTGYNRLMIEKPFGTSYDTAAELQNDLENAFDDNQLFRIDHYLGKEMVQNIAALRFGNPIFDAAWNKDYIKNVQVTLSEVLGVEERAGYYDTAGALLDMIQNHTMQIVGWLAMEKPESFTDKDIRAAKNAAFNALKIYDEAEVNKYFVRAQYGAGDSADFKPYLEELDVPADSKNNTFIAGELQFDLPRWEGVPFYVRSGKRLAAKQTRVDIVFKAGTFNFGSEQEAQEAVLSIIIDPKGAIELKLNAKSVEDAFNTRTIDLGWTVSDEDKKNTPEPYERMIHDTMNGDGSNFADWNGVSIAWKFVDAISAVYTADKAPLETYKSGSMGPEASDKLLAANGDAWVFKG
  
Inhibitor
Name:
BDBM62014
Synonyms:
4-bromanyl-2-[(4-methoxyphenyl)carbonylamino]benzoic acid | 4-bromo-2-(p-anisoylamino)benzoic acid | 4-bromo-2-[(4-methoxybenzoyl)amino]benzoic acid | 4-bromo-2-[[(4-methoxyphenyl)-oxomethyl]amino]benzoic acid | KSC-18-008 | KUC105928N | cid_46245547
Type:
Small organic molecule
Emp. Form.:
C15H12BrNO4
Mol. Mass.:
350.164
SMILES:
COc1ccc(cc1)C(=O)Nc1cc(Br)ccc1C(O)=O
Structure:
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