Reaction Details Report a problem with these data
Target
Glucose-6-phosphate 1-dehydrogenase
Ligand
BDBM62051
Substrate
n/a
Meas. Tech.
G6DPH counterscreen for TbHK1 inhibitors - Analogues series
IC50
>25000±n/a nM
Citation
 PubChem, PC G6DPH counterscreen for TbHK1 inhibitors - Analogues series PubChem Bioassay (2010)[AID] 
Target
Name:
Glucose-6-phosphate 1-dehydrogenase
Synonyms:
G6PD_LEUME | glucose-6-phosphate dehydrogenase | zwf
Type:
Enzyme Catalytic Domain
Mol. Mass.:
54421.26
Organism:
Leuconostoc mesenteroides
Description:
gi_149631
Residue:
486
Sequence:
MVSEIKTLVTFFGGTGDLAKRKLYPSVFNLYKKGYLQKHFAIVGTARQALNDDEFKQLVRDSIKDFTDDQAQAEAFIEHFSYRAHDVTDAASYAVLKEAIEEAADKFDIDGNRIFYMSVAPRFFGTIAKYLKSEGLLADTGYNRLMIEKPFGTSYDTAAELQNDLENAFDDNQLFRIDHYLGKEMVQNIAALRFGNPIFDAAWNKDYIKNVQVTLSEVLGVEERAGYYDTAGALLDMIQNHTMQIVGWLAMEKPESFTDKDIRAAKNAAFNALKIYDEAEVNKYFVRAQYGAGDSADFKPYLEELDVPADSKNNTFIAGELQFDLPRWEGVPFYVRSGKRLAAKQTRVDIVFKAGTFNFGSEQEAQEAVLSIIIDPKGAIELKLNAKSVEDAFNTRTIDLGWTVSDEDKKNTPEPYERMIHDTMNGDGSNFADWNGVSIAWKFVDAISAVYTADKAPLETYKSGSMGPEASDKLLAANGDAWVFKG
  
Inhibitor
Name:
BDBM62051
Synonyms:
2-[(4-benzylbenzoyl)amino]-4-chloro-benzoic acid | 2-[(4-benzylbenzoyl)amino]-4-chlorobenzoic acid | 4-chloranyl-2-[[4-(phenylmethyl)phenyl]carbonylamino]benzoic acid | 4-chloro-2-[[oxo-[4-(phenylmethyl)phenyl]methyl]amino]benzoic acid | KSC-20-020 | KUC106490N | cid_46856248
Type:
Small organic molecule
Emp. Form.:
C21H16ClNO3
Mol. Mass.:
365.81
SMILES:
OC(=O)c1ccc(Cl)cc1NC(=O)c1ccc(Cc2ccccc2)cc1
Structure:
Search PDB for entries with ligand similarity: