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Target
Potassium voltage-gated channel subfamily KQT member 2
Ligand
BDBM65878
Substrate
n/a
Meas. Tech.
Mode of action assay-Automated electrophysiology assay of compounds that potentiate KCNQ2 potassium channel
EC50
12030±3660 nM
Citation
 PubChem, PC Mode of action assay-Automated electrophysiology assay of compounds that potentiate KCNQ2 potassium channel PubChem Bioassay (2010)[AID] 
Target
Name:
Potassium voltage-gated channel subfamily KQT member 2
Synonyms:
KCNQ2_RAT | Kcnq2 | Voltage-gated potassium channel subunit Kv7.2 | potassium voltage-gated channel, KQT-like subfamily, member 2
Type:
PROTEIN
Mol. Mass.:
93984.01
Organism:
Rattus norvegicus
Description:
EBI_100117
Residue:
852
Sequence:
MVQKSRNGGVYPGTSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSVLSKPRTGGAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMISSQTQTYGASRLIPPLNQLEMLRNLKSKSGLTFRKEPQPEPSPSQKVSLKDRVFSSPRGVAAKGKGSPQAQTVRRSPSADQSLDDSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSEEASLPGEDIVEDNKSCNCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPTITDKDRTKGPAETELPEDPSMMGRLGKVEKQVLSMEKKLDFLVSIYTQRMGIPPAETEAYFGAKEPEPAPPYHSPEDSRDHADKHGCIIKIVRSTSSTGQRKYAAPPVMPPAECPPSTSWQQSHQRHGTSPVGDHGSLVRIPPPPAHERSLSAYSGGNRASTEFLRLEGTPACRPSEAALRDSDTSISIPSVDHEELERSFSGFSISQSKENLNALASCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATGEGPFGDVAWAGPRK
  
Inhibitor
Name:
BDBM65878
Synonyms:
MLS000547588 | N-(4-naphthalen-2-yloxyphenyl)furan-2-carboxamide | N-[4-(2-naphthalenyloxy)phenyl]-2-furancarboxamide | N-[4-(2-naphthoxy)phenyl]-2-furamide | N-[4-(2-naphthyloxy)phenyl]-2-furamide | SMR000114699 | cid_902659
Type:
Small organic molecule
Emp. Form.:
C21H15NO3
Mol. Mass.:
329.3487
SMILES:
O=C(Nc1ccc(Oc2ccc3ccccc3c2)cc1)c1ccco1
Structure:
Search PDB for entries with ligand similarity: