Reaction Details Report a problem with these data
Target
60S ribosomal protein L19-A
Ligand
BDBM66000
Substrate
n/a
Meas. Tech.
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits
EC50
26780±n/a nM
Citation
 PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits PubChem Bioassay (2010)[AID] 
Target
Name:
60S ribosomal protein L19-A
Synonyms:
RL19A_YEAST | RPL19A | RPL23A | YL14A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21739.62
Organism:
Saccharomyces cerevisiae
Description:
gi_536029
Residue:
189
Sequence:
MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEARRLKNRAARDRRAQRVAEKRDALLKEDA
  
Inhibitor
Name:
BDBM66000
Synonyms:
(E)-1-(4-bromanyl-2-oxidanyl-phenyl)-3-pyridin-2-yl-prop-2-en-1-one | (E)-1-(4-bromo-2-hydroxy-phenyl)-3-(2-pyridyl)prop-2-en-1-one | (E)-1-(4-bromo-2-hydroxyphenyl)-3-(2-pyridinyl)-2-propen-1-one | (E)-1-(4-bromo-2-hydroxyphenyl)-3-pyridin-2-ylprop-2-en-1-one | MLS000704465 | SMR000231558 | cid_6263971
Type:
Small organic molecule
Emp. Form.:
C14H10BrNO2
Mol. Mass.:
304.139
SMILES:
Oc1cc(Br)ccc1C(=O)\C=C\c1ccccn1
Structure:
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