Reaction Details Report a problem with these data
Target
60S ribosomal protein L19-A
Ligand
BDBM66015
Substrate
n/a
Meas. Tech.
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits
EC50
11750±n/a nM
Citation
 PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits PubChem Bioassay (2010)[AID] 
Target
Name:
60S ribosomal protein L19-A
Synonyms:
RL19A_YEAST | RPL19A | RPL23A | YL14A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21739.62
Organism:
Saccharomyces cerevisiae
Description:
gi_536029
Residue:
189
Sequence:
MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEARRLKNRAARDRRAQRVAEKRDALLKEDA
  
Inhibitor
Name:
BDBM66015
Synonyms:
5-nitro-2-[3-(trifluoromethyl)phenyl]sulfonyl-pyridine | 5-nitro-2-[3-(trifluoromethyl)phenyl]sulfonylpyridine | 5-nitro-2-{[3-(trifluoromethyl)phenyl]sulfonyl}pyridine | MLS001178404 | SMR000476527 | cid_901998
Type:
Small organic molecule
Emp. Form.:
C12H7F3N2O4S
Mol. Mass.:
332.255
SMILES:
[O-][N+](=O)c1ccc(nc1)S(=O)(=O)c1cccc(c1)C(F)(F)F
Structure:
Search PDB for entries with ligand similarity: