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Target
Vacuolar aminopeptidase 1
Ligand
BDBM65005
Substrate
n/a
Meas. Tech.
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically LAP4 based on MLPCN hits
EC50
17800±n/a nM
Citation
 PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically LAP4 based on MLPCN hits PubChem Bioassay (2010)[AID] 
Target
Name:
Vacuolar aminopeptidase 1
Synonyms:
AMPL_YEAST | APE1 | API | LAP4 | YSC1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57084.90
Organism:
Saccharomyces cerevisiae
Description:
gi_486173
Residue:
514
Sequence:
MEEQREILEQLKKTLQMLTVEPSKNNQIANEEKEKKENENSWCILEHNYEDIAQEFIDFIYKNPTTYHVVSFFAELLDKHNFKYLSEKSNWQDSIGEDGGKFYTIRNGTNLSAFILGKNWRAEKGVGVIGSHVDALTVKLKPVSFKDTAEGYGRIAVAPYGGTLNELWLDRDLGIGGRLLYKKKGTNEIKSALVDSTPLPVCRIPSLAPHFGKPAEGPFDKEDQTIPVIGFPTPDEEGNEPPTDDEKKSPLFGKHCIHLLRYVAKLAGVEVSELIQMDLDLFDVQKGTIGGIGKHFLFAPRLDDRLCSFAAMIALICYAKDVNTEESDLFSTVTLYDNEEIGSLTRQGAKGGLLESVVERSSSAFTKKPVDLHTVWANSIILSADVNHLYNPNFPEVYLKNHFPVPNVGITLSLDPNGHMATDVVGTALVEELARRNGDKVQYFQIKNNSRSGGTIGPSLASQTGARTIDLGIAQLSMHSIRAATGSKDVGLGVKFFNGFFKHWRSVYDEFGEL
  
Inhibitor
Name:
BDBM65005
Synonyms:
2,4-bis(chloranyl)-N-[(2-phenoxyethanoylamino)carbamothioyl]benzamide | 2,4-dichloro-N-[[(1-oxo-2-phenoxyethyl)hydrazo]-sulfanylidenemethyl]benzamide | 2,4-dichloro-N-[[(2-phenoxyacetyl)amino]carbamothioyl]benzamide | 2,4-dichloro-N-[[(2-phenoxyacetyl)amino]thiocarbamoyl]benzamide | 2,4-dichloro-N-{[2-(phenoxyacetyl)hydrazino]carbothioyl}benzamide | MLS000547963 | SMR000115205 | cid_1790614
Type:
Small organic molecule
Emp. Form.:
C16H13Cl2N3O3S
Mol. Mass.:
398.264
SMILES:
Clc1ccc(C(=O)NC(=S)NNC(=O)COc2ccccc2)c(Cl)c1
Structure:
Search PDB for entries with ligand similarity: