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Target
Vacuolar aminopeptidase 1
Ligand
BDBM65984
Substrate
n/a
Meas. Tech.
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically LAP4 based on MLPCN hits
EC50
4397±n/a nM
Citation
 PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically LAP4 based on MLPCN hits PubChem Bioassay (2010)[AID] 
Target
Name:
Vacuolar aminopeptidase 1
Synonyms:
AMPL_YEAST | APE1 | API | LAP4 | YSC1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57084.90
Organism:
Saccharomyces cerevisiae
Description:
gi_486173
Residue:
514
Sequence:
MEEQREILEQLKKTLQMLTVEPSKNNQIANEEKEKKENENSWCILEHNYEDIAQEFIDFIYKNPTTYHVVSFFAELLDKHNFKYLSEKSNWQDSIGEDGGKFYTIRNGTNLSAFILGKNWRAEKGVGVIGSHVDALTVKLKPVSFKDTAEGYGRIAVAPYGGTLNELWLDRDLGIGGRLLYKKKGTNEIKSALVDSTPLPVCRIPSLAPHFGKPAEGPFDKEDQTIPVIGFPTPDEEGNEPPTDDEKKSPLFGKHCIHLLRYVAKLAGVEVSELIQMDLDLFDVQKGTIGGIGKHFLFAPRLDDRLCSFAAMIALICYAKDVNTEESDLFSTVTLYDNEEIGSLTRQGAKGGLLESVVERSSSAFTKKPVDLHTVWANSIILSADVNHLYNPNFPEVYLKNHFPVPNVGITLSLDPNGHMATDVVGTALVEELARRNGDKVQYFQIKNNSRSGGTIGPSLASQTGARTIDLGIAQLSMHSIRAATGSKDVGLGVKFFNGFFKHWRSVYDEFGEL
  
Inhibitor
Name:
BDBM65984
Synonyms:
MLS000534613 | N'-(benzoyloxy)-2-(4-chlorophenyl)ethanimidamide | SMR000142050 | [(Z)-[1-amino-2-(4-chlorophenyl)ethylidene]amino] benzoate | [(Z)-[1-azanyl-2-(4-chlorophenyl)ethylidene]amino] benzoate | benzoic acid [(Z)-[1-amino-2-(4-chlorophenyl)ethylidene]amino] ester | cid_5893661
Type:
Small organic molecule
Emp. Form.:
C15H13ClN2O2
Mol. Mass.:
288.729
SMILES:
NC(Cc1ccc(Cl)cc1)=NOC(=O)c1ccccc1 |w:10.11|
Structure:
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