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Target
Vacuolar aminopeptidase 1
Ligand
BDBM65522
Substrate
n/a
Meas. Tech.
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically LAP4 based on MLPCN hits
EC50
>33000±n/a nM
Citation
 PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically LAP4 based on MLPCN hits PubChem Bioassay (2010)[AID] 
Target
Name:
Vacuolar aminopeptidase 1
Synonyms:
AMPL_YEAST | APE1 | API | LAP4 | YSC1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57084.90
Organism:
Saccharomyces cerevisiae
Description:
gi_486173
Residue:
514
Sequence:
MEEQREILEQLKKTLQMLTVEPSKNNQIANEEKEKKENENSWCILEHNYEDIAQEFIDFIYKNPTTYHVVSFFAELLDKHNFKYLSEKSNWQDSIGEDGGKFYTIRNGTNLSAFILGKNWRAEKGVGVIGSHVDALTVKLKPVSFKDTAEGYGRIAVAPYGGTLNELWLDRDLGIGGRLLYKKKGTNEIKSALVDSTPLPVCRIPSLAPHFGKPAEGPFDKEDQTIPVIGFPTPDEEGNEPPTDDEKKSPLFGKHCIHLLRYVAKLAGVEVSELIQMDLDLFDVQKGTIGGIGKHFLFAPRLDDRLCSFAAMIALICYAKDVNTEESDLFSTVTLYDNEEIGSLTRQGAKGGLLESVVERSSSAFTKKPVDLHTVWANSIILSADVNHLYNPNFPEVYLKNHFPVPNVGITLSLDPNGHMATDVVGTALVEELARRNGDKVQYFQIKNNSRSGGTIGPSLASQTGARTIDLGIAQLSMHSIRAATGSKDVGLGVKFFNGFFKHWRSVYDEFGEL
  
Inhibitor
Name:
BDBM65522
Synonyms:
(E)-3-(5-Bromo-2-hydroxy-phenyl)-1-furan-2-yl-propenone | (E)-3-(5-bromanyl-2-oxidanyl-phenyl)-1-(furan-2-yl)prop-2-en-1-one | (E)-3-(5-bromo-2-hydroxy-phenyl)-1-(2-furyl)prop-2-en-1-one | (E)-3-(5-bromo-2-hydroxyphenyl)-1-(2-furanyl)-2-propen-1-one | (E)-3-(5-bromo-2-hydroxyphenyl)-1-(furan-2-yl)prop-2-en-1-one | MLS000806912 | SMR000414771 | cid_5852959
Type:
Small organic molecule
Emp. Form.:
C13H9BrO3
Mol. Mass.:
293.113
SMILES:
Oc1ccc(Br)cc1\C=C\C(=O)c1ccco1
Structure:
Search PDB for entries with ligand similarity: