Reaction Details Report a problem with these data
Target
Photoreceptor-specific nuclear receptor
Ligand
BDBM37784
Substrate
n/a
Meas. Tech.
TR-FRET-based biochemical high throughput dose response assay for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3)
IC50
>39841±n/a nM
Citation
 PubChem, PC TR-FRET-based biochemical high throughput dose response assay for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3) PubChem Bioassay (2010)[AID] 
Target
Name:
Photoreceptor-specific nuclear receptor
Synonyms:
NR2E3 | NR2E3_HUMAN | PNR | RNR | photoreceptor-specific nuclear receptor
Type:
PROTEIN
Mol. Mass.:
44699.83
Organism:
Homo sapiens (Human)
Description:
ChEMBL_401901
Residue:
410
Sequence:
METRPTALMSSTVAAAAPAAGAASRKESPGRWGLGEDPTGVSPSLQCRVCGDSSSGKHYGIYACNGCSGFFKRSVRRRLIYRCQVGAGMCPVDKAHRNQCQACRLKKCLQAGMNQDAVQNERQPRSTAQVHLDSMESNTESRPESLVAPPAPAGRSPRGPTPMSAARALGHHFMASLITAETCAKLEPEDADENIDVTSNDPEFPSSPYSSSSPCGLDSIHETSARLLFMAVKWAKNLPVFSSLPFRDQVILLEEAWSELFLLGAIQWSLPLDSCPLLAPPEASAAGGAQGRLTLASMETRVLQETISRFRALAVDPTEFACMKALVLFKPETRGLKDPEHVEALQDQSQVMLSQHSKAHHPSQPVRFGKLLLLLPSLRFITAERIELLFFRKTIGNTPMEKLLCDMFKN
  
Inhibitor
Name:
BDBM37784
Synonyms:
1-(2-furanylmethyl)-4-hydroxy-3-[(7-methoxy-2-benzofuranyl)-oxomethyl]-2-(3-pyridinyl)-2H-pyrrol-5-one | 1-(2-furfuryl)-3-hydroxy-4-(7-methoxybenzofuran-2-carbonyl)-5-(3-pyridyl)-3-pyrrolin-2-one | 1-(2-furylmethyl)-3-hydroxy-4-[(7-methoxy-1-benzofuran-2-yl)carbonyl]-5-(3-pyridinyl)-1,5-dihydro-2H-pyrrol-2-one | 1-(furan-2-ylmethyl)-3-[(7-methoxy-1-benzofuran-2-yl)carbonyl]-4-oxidanyl-2-pyridin-3-yl-2H-pyrrol-5-one | 1-(furan-2-ylmethyl)-4-hydroxy-3-(7-methoxy-1-benzofuran-2-carbonyl)-2-pyridin-3-yl-2H-pyrrol-5-one | MLS000097076 | SMR000075743 | cid_2951279
Type:
Small organic molecule
Emp. Form.:
C24H18N2O6
Mol. Mass.:
430.4095
SMILES:
COc1cccc2cc(oc12)C(=O)C1C(N(Cc2ccco2)C(=O)C1=O)c1cccnc1
Structure:
Search PDB for entries with ligand similarity: