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Target
Photoreceptor-specific nuclear receptor
Ligand
BDBM66166
Substrate
n/a
Meas. Tech.
TR-FRET-based biochemical high throughput dose response assay for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3)
IC50
>39841±n/a nM
Citation
 PubChem, PC TR-FRET-based biochemical high throughput dose response assay for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3) PubChem Bioassay (2010)[AID] 
Target
Name:
Photoreceptor-specific nuclear receptor
Synonyms:
NR2E3 | NR2E3_HUMAN | PNR | RNR | photoreceptor-specific nuclear receptor
Type:
PROTEIN
Mol. Mass.:
44699.83
Organism:
Homo sapiens (Human)
Description:
ChEMBL_401901
Residue:
410
Sequence:
METRPTALMSSTVAAAAPAAGAASRKESPGRWGLGEDPTGVSPSLQCRVCGDSSSGKHYGIYACNGCSGFFKRSVRRRLIYRCQVGAGMCPVDKAHRNQCQACRLKKCLQAGMNQDAVQNERQPRSTAQVHLDSMESNTESRPESLVAPPAPAGRSPRGPTPMSAARALGHHFMASLITAETCAKLEPEDADENIDVTSNDPEFPSSPYSSSSPCGLDSIHETSARLLFMAVKWAKNLPVFSSLPFRDQVILLEEAWSELFLLGAIQWSLPLDSCPLLAPPEASAAGGAQGRLTLASMETRVLQETISRFRALAVDPTEFACMKALVLFKPETRGLKDPEHVEALQDQSQVMLSQHSKAHHPSQPVRFGKLLLLLPSLRFITAERIELLFFRKTIGNTPMEKLLCDMFKN
  
Inhibitor
Name:
BDBM66166
Synonyms:
2-(3-Ethyl-thioureido)-5,6,7,8-tetrahydro-quinoline-3-carboxylic acid ethyl ester | 2-(ethylthiocarbamoylamino)-5,6,7,8-tetrahydroquinoline-3-carboxylic acid ethyl ester | 2-[[ethylamino(sulfanylidene)methyl]amino]-5,6,7,8-tetrahydroquinoline-3-carboxylic acid ethyl ester | MLS000589165 | SMR000219774 | cid_4302834 | ethyl 2-(ethylcarbamothioylamino)-5,6,7,8-tetrahydroquinoline-3-carboxylate
Type:
Small organic molecule
Emp. Form.:
C15H21N3O2S
Mol. Mass.:
307.411
SMILES:
CCNC(=S)Nc1nc2CCCCc2cc1C(=O)OCC
Structure:
Search PDB for entries with ligand similarity: