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Target
Bcl-2-like protein 11
Ligand
BDBM66475
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
EC50
>350000±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay (2010)[AID] 
Target
Name:
Bcl-2-like protein 11
Synonyms:
B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM
Type:
PROTEIN
Mol. Mass.:
22175.26
Organism:
Homo sapiens (Human)
Description:
EBI_101325
Residue:
198
Sequence:
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH
  
Inhibitor
Name:
BDBM66475
Synonyms:
5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-2-carboxylic acid (1-allophanoyl-2-methyl-propyl) ester | 5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-2-carboxylic acid [1-(carbamoylamino)-3-methyl-1-oxobutan-2-yl] ester | MLS000417714 | SMR000264664 | [1-(aminocarbonylamino)-3-methyl-1-oxidanylidene-butan-2-yl] 5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-2-carboxylate | [1-(carbamoylamino)-3-methyl-1-oxobutan-2-yl] 5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-2-carboxylate | cid_4883633
Type:
Small organic molecule
Emp. Form.:
C16H22N2O4S
Mol. Mass.:
338.422
SMILES:
CC(C)C(OC(=O)c1cc2CCCCCc2s1)C(=O)NC(N)=O
Structure:
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