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Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM67094
Substrate
n/a
Meas. Tech.
Late stage counterscreen results from the probe development effort to identify STAT1 inhibitors: luminescence-based cell-based dose response assay for STAT3 inhibitors
IC50
>55690±n/a nM
Citation
 PubChem, PC Late stage counterscreen results from the probe development effort to identify STAT1 inhibitors: luminescence-based cell-based dose response assay for STAT3 inhibitors PubChem Bioassay (2010)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM67094
Synonyms:
3-[4-[4-(2-furoyl)piperazine-1-carbonyl]phenyl]-2-thioxo-1H-quinazolin-4-one | 3-[4-[4-(furan-2-carbonyl)piperazine-1-carbonyl]phenyl]-2-sulfanylidene-1H-quinazolin-4-one | 3-[4-[4-(furan-2-ylcarbonyl)piperazin-1-yl]carbonylphenyl]-2-sulfanylidene-1H-quinazolin-4-one | 3-[4-[[4-[2-furanyl(oxo)methyl]-1-piperazinyl]-oxomethyl]phenyl]-2-sulfanylidene-1H-quinazolin-4-one | SR-01000557778-2 | cid_3633039
Type:
Small organic molecule
Emp. Form.:
C24H20N4O4S
Mol. Mass.:
460.505
SMILES:
O=C(N1CCN(CC1)C(=O)c1ccc(cc1)-n1c(=S)[nH]c2ccccc2c1=O)c1ccco1
Structure:
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