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Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM67098
Substrate
n/a
Meas. Tech.
Late stage counterscreen results from the probe development effort to identify STAT1 inhibitors: luminescence-based cell-based dose response assay for STAT3 inhibitors
IC50
>55690±n/a nM
Citation
 PubChem, PC Late stage counterscreen results from the probe development effort to identify STAT1 inhibitors: luminescence-based cell-based dose response assay for STAT3 inhibitors PubChem Bioassay (2010)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM67098
Synonyms:
3-[4-[4-(4-methoxyphenyl)piperazin-1-yl]carbonylphenyl]-2-sulfanylidene-1H-quinazolin-4-one | 3-[4-[4-(4-methoxyphenyl)piperazine-1-carbonyl]phenyl]-2-sulfanylidene-1H-quinazolin-4-one | 3-[4-[4-(4-methoxyphenyl)piperazine-1-carbonyl]phenyl]-2-thioxo-1H-quinazolin-4-one | 3-[4-[[4-(4-methoxyphenyl)-1-piperazinyl]-oxomethyl]phenyl]-2-sulfanylidene-1H-quinazolin-4-one | SR-01000563082-2 | cid_4583088
Type:
Small organic molecule
Emp. Form.:
C26H24N4O3S
Mol. Mass.:
472.559
SMILES:
COc1ccc(cc1)N1CCN(CC1)C(=O)c1ccc(cc1)-n1c(=S)[nH]c2ccccc2c1=O
Structure:
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