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Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM67103
Substrate
n/a
Meas. Tech.
Late stage counterscreen results from the probe development effort to identify STAT1 inhibitors: luminescence-based cell-based dose response assay for STAT3 inhibitors
IC50
>55690±n/a nM
Citation
 PubChem, PC Late stage counterscreen results from the probe development effort to identify STAT1 inhibitors: luminescence-based cell-based dose response assay for STAT3 inhibitors PubChem Bioassay (2010)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM67103
Synonyms:
2-[(dimethylamino)methyl]-3-[[4-(3-nitrophenyl)-1,3-thiazol-2-yl]methyl]quinazolin-4-one | 2-[(dimethylamino)methyl]-3-[[4-(3-nitrophenyl)-2-thiazolyl]methyl]-4-quinazolinone | 2-[(dimethylamino)methyl]-3-[[4-(3-nitrophenyl)thiazol-2-yl]methyl]quinazolin-4-one | SR-01000741204-2 | cid_2086912
Type:
Small organic molecule
Emp. Form.:
C21H19N5O3S
Mol. Mass.:
421.472
SMILES:
CN(C)Cc1nc2ccccc2c(=O)n1Cc1nc(cs1)-c1cccc(c1)[N+]([O-])=O
Structure:
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