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Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM67123
Substrate
n/a
Meas. Tech.
Late stage counterscreen results from the probe development effort to identify STAT1 inhibitors: luminescence-based cell-based dose response assay for STAT3 inhibitors
IC50
>55690±n/a nM
Citation
 PubChem, PC Late stage counterscreen results from the probe development effort to identify STAT1 inhibitors: luminescence-based cell-based dose response assay for STAT3 inhibitors PubChem Bioassay (2010)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM67123
Synonyms:
3-(3-chloranyl-4-methyl-phenyl)-4-oxidanylidene-phthalazine-1-carboxylic acid | 3-(3-chloro-4-methyl-phenyl)-4-keto-phthalazine-1-carboxylic acid | 3-(3-chloro-4-methylphenyl)-4-oxo-1-phthalazinecarboxylic acid | 3-(3-chloro-4-methylphenyl)-4-oxophthalazine-1-carboxylic acid | SR-03000000792-1 | cid_16776203
Type:
Small organic molecule
Emp. Form.:
C16H11ClN2O3
Mol. Mass.:
314.723
SMILES:
Cc1ccc(cc1Cl)-n1nc(C(O)=O)c2ccccc2c1=O
Structure:
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