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Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM67128
Substrate
n/a
Meas. Tech.
Late stage counterscreen results from the probe development effort to identify STAT1 inhibitors: luminescence-based cell-based dose response assay for STAT3 inhibitors
IC50
>55690±n/a nM
Citation
 PubChem, PC Late stage counterscreen results from the probe development effort to identify STAT1 inhibitors: luminescence-based cell-based dose response assay for STAT3 inhibitors PubChem Bioassay (2010)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM67128
Synonyms:
2-[(6-chloranyl-7-methyl-2-oxidanylidene-chromen-4-yl)methylsulfanyl]-1H-quinazolin-4-one | 2-[(6-chloro-2-keto-7-methyl-chromen-4-yl)methylthio]-1H-quinazolin-4-one | 2-[(6-chloro-7-methyl-2-oxo-1-benzopyran-4-yl)methylthio]-1H-quinazolin-4-one | 2-[(6-chloro-7-methyl-2-oxochromen-4-yl)methylsulfanyl]-1H-quinazolin-4-one | SR-03000000853-1 | cid_2475889
Type:
Small organic molecule
Emp. Form.:
C19H13ClN2O3S
Mol. Mass.:
384.836
SMILES:
Cc1cc2oc(=O)cc(CSc3nc4ccccc4c(=O)[nH]3)c2cc1Cl
Structure:
Search PDB for entries with ligand similarity: