Reaction Details Report a problem with these data
Target
NADPH oxidase 1
Ligand
BDBM67526
Substrate
n/a
Meas. Tech.
Late-stage luminescence-based cell-based dose response assay to identify inhibitors of NADPH oxidase 1 (NOX1): Purchased analogs
IC50
>17000±n/a nM
Citation
 PubChem, PC Late-stage luminescence-based cell-based dose response assay to identify inhibitors of NADPH oxidase 1 (NOX1): Purchased analogs PubChem Bioassay (2010)[AID] 
Target
Name:
NADPH oxidase 1
Synonyms:
MOX-1 | MOX1 | Mitogenic oxidase 1 | NADH/NADPH mitogenic oxidase subunit P65-MOX | NOH-1 | NOH1 | NOX-1 | NOX1 | NOX1_HUMAN
Type:
PROTEIN
Mol. Mass.:
64890.44
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792877
Residue:
564
Sequence:
MGNWVVNHWFSVLFLVVWLGLNVFLFVDAFLKYEKADKYYYTRKILGSTLACARASALCLNFNSTLILLPVCRNLLSFLRGTCSFCSRTLRKQLDHNLTFHKLVAYMICLHTAIHIIAHLFNFDCYSRSRQATDGSLASILSSLSHDEKKGGSWLNPIQSRNTTVEYVTFTSIAGLTGVIMTIALILMVTSATEFIRRSYFEVFWYTHHLFIFYILGLGIHGIGGIVRGQTEESMNESHPRKCAESFEMWDDRDSHCRRPKFEGHPPESWKWILAPVILYICERILRFYRSQQKVVITKVVMHPSKVLELQMNKRGFSMEVGQYIFVNCPSISLLEWHPFTLTSAPEEDFFSIHIRAAGDWTENLIRAFEQQYSPIPRIEVDGPFGTASEDVFQYEVAVLVGAGIGVTPFASILKSIWYKFQCADHNLKTKKIYFYWICRETGAFSWFNNLLTSLEQEMEELGKVGFLNYRLFLTGWDSNIVGHAALNFDKATDIVTGLKQKTSFGRPMWDNEFSTIATSHPKSVVGVFLCGPRTLAKSLRKCCHRYSSLDPRKVQFYFNKENF
  
Inhibitor
Name:
BDBM67526
Synonyms:
3-chloro-1-benzothiophene-2-carboxylic acid [4-(1,3,4-oxadiazol-2-yl)phenyl] ester | 3-chlorobenzothiophene-2-carboxylic acid [4-(1,3,4-oxadiazol-2-yl)phenyl] ester | SR-03000000748-1 | [4-(1,3,4-oxadiazol-2-yl)phenyl] 3-chloranyl-1-benzothiophene-2-carboxylate | [4-(1,3,4-oxadiazol-2-yl)phenyl] 3-chloro-1-benzothiophene-2-carboxylate | cid_8893713
Type:
Small organic molecule
Emp. Form.:
C17H9ClN2O3S
Mol. Mass.:
356.783
SMILES:
Clc1c(sc2ccccc12)C(=O)Oc1ccc(cc1)-c1nnco1
Structure:
Search PDB for entries with ligand similarity: