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Target
Serine/threonine-protein phosphatase
Ligand
BDBM64768
Substrate
n/a
Meas. Tech.
Fluorescence Cell-Based Secondary Assay to Identify Inhibitors of Calcineurin
EC50
9763±n/a nM
Citation
 PubChem, PC Fluorescence Cell-Based Secondary Assay to Identify Inhibitors of Calcineurin PubChem Bioassay (2010)[AID] 
Target
Name:
Serine/threonine-protein phosphatase
Synonyms:
calcineurin A1, putative | calmodulin-binding protein 1, putative | serine/threonine-protein phosphatase 2B catalytic subunit A1, putative
Type:
Enzyme Catalytic Domain
Mol. Mass.:
69558.03
Organism:
Candida dubliniensis CD36
Description:
gi_223640082
Residue:
607
Sequence:
MSGNTVQRNTEQINNALNAIQHRRTTTGNDLNHTNQRIISQNSINDKDYTIYITDDGEKYSTVERAVKSVDPPVTFKPKDEQVFLSNGKPNHQFLKQHFIHEGRLHEHQAIQILKQATHLLSKESNLLNVPAPVTICGDVHGQYYDLMKLFEVGGDPATTKYLFLGDYVDRGSFSIECLLYLYSLKINYPDTFWMLRGNHECRHLTEYFTFKNECLHKYSEQLYEECLVSFNALPLAAIMNEQFFCVHGGLSPQLTSLDSLRKLHRFREPPTKGLMCDLLWADPIEEYDEDNIDQEYVTNVVRGCSFAFTYKAACKFLDKTKLLSVIRAHEAQNAGYRMYKRTKTMGFPSLLTMFSAPNYLDSYNNKAAVLKYENNVMNIRQFNASPHPYWLPHFMDVFTWSLPFVGEKVTDMLVSILNVCTEEELDEDLPFSESEIGVATKTTKTTTPVSPVSPKAHPPSTRITSPYKSTKLVESDNNPNTNNDDSEMTLEEKKQALRNKIIAIGKMSRMFQVLREEQENVAHLKELNRGSLPKGSLLHGVDGLKNTINSFEEAKAADRINEALPPSPEDIQRLKQEKNTRIRQQIENQEMSGPVFQRLIRRLSQS
  
Inhibitor
Name:
BDBM64768
Synonyms:
4,5,6,7-tetrafluoro-2-methyl-N-[3-(trifluoromethyl)phenyl]-1-benzofuran-3-sulfonamide | 4,5,6,7-tetrafluoro-2-methyl-N-[3-(trifluoromethyl)phenyl]-3-benzofuransulfonamide | 4,5,6,7-tetrafluoro-2-methyl-N-[3-(trifluoromethyl)phenyl]benzofuran-3-sulfonamide | 4,5,6,7-tetrakis(fluoranyl)-2-methyl-N-[3-(trifluoromethyl)phenyl]-1-benzofuran-3-sulfonamide | MLS001098049 | N3-[3-(trifluoromethyl)phenyl]-4,5,6,7-tetrafluoro-2-methylbenzo[b]furan-3-sulfonamide | SMR000657733 | cid_2739954
Type:
Small organic molecule
Emp. Form.:
C16H8F7NO3S
Mol. Mass.:
427.293
SMILES:
Cc1oc2c(F)c(F)c(F)c(F)c2c1S(=O)(=O)Nc1cccc(c1)C(F)(F)F
Structure:
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