Reaction Details Report a problem with these data
Target
Protein Rev
Ligand
BDBM51080
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction
IC50
>75386±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction PubChem Bioassay (2010)[AID] 
Target
Name:
Protein Rev
Synonyms:
Human immunodeficiency virus type 1 REV | REV_HV1H2 | rev
Type:
PROTEIN
Mol. Mass.:
13078.11
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_79479
Residue:
116
Sequence:
MAGRSGDSDEELIRTVRLIKLLYQSNPPPNPEGTRQARRNRRRRWRERQRQIHSISERILGTYLGRSAEPVPLQLPPLERLTLDCNEDCGTSGTQGVGSPQILVESPTVLESGTKE
  
Inhibitor
Name:
BDBM51080
Synonyms:
4-[(2Z)-2-(2-oxo-1-naphthalenylidene)hydrazinyl]-1H-imidazole-5-carboxylic acid ethyl ester | 4-[(N'Z)-N'-(2-keto-1-naphthylidene)hydrazino]-1H-imidazole-5-carboxylic acid ethyl ester | MLS000705197 | SMR000231024 | cid_6078945 | ethyl 4-[(2Z)-2-(2-oxidanylidenenaphthalen-1-ylidene)hydrazinyl]-1H-imidazole-5-carboxylate | ethyl 4-[(2Z)-2-(2-oxonaphthalen-1-ylidene)hydrazinyl]-1H-imidazole-5-carboxylate | ethyl 5-[(2-hydroxy-1-naphthyl)diazenyl]-1H-imidazole-4-carboxylate
Type:
Small organic molecule
Emp. Form.:
C16H14N4O3
Mol. Mass.:
310.3074
SMILES:
CCOC(=O)c1[nH]cnc1N=Nc1c(O)ccc2ccccc12 |w:10.10|
Structure:
Search PDB for entries with ligand similarity: