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Target
Tyrosine-protein phosphatase non-receptor type 7
Ligand
BDBM74446
Substrate
n/a
Meas. Tech.
Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2
IC50
>79400±0 nM
Citation
 PubChem, PC Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2 PubChem Bioassay (2010)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 7
Synonyms:
He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:
Protein
Mol. Mass.:
40530.79
Organism:
Homo sapiens (Human)
Description:
P35236
Residue:
360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
  
Inhibitor
Name:
BDBM74446
Synonyms:
4-(2-thenylsulfamoyl)-N-thiazol-2-yl-benzamide | MLS000026813 | N-(1,3-thiazol-2-yl)-4-(thiophen-2-ylmethylsulfamoyl)benzamide | N-(2-thiazolyl)-4-(thiophen-2-ylmethylsulfamoyl)benzamide | N-Thiazol-2-yl-4-[(thiophen-2-ylmethyl)-sulfamoyl]-benzamide | SMR000003930 | cid_649089
Type:
Small organic molecule
Emp. Form.:
C15H13N3O3S3
Mol. Mass.:
379.477
SMILES:
O=C(Nc1nccs1)c1ccc(cc1)S(=O)(=O)NCc1cccs1
Structure:
Search PDB for entries with ligand similarity: