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Target
Tyrosine-protein phosphatase non-receptor type 7
Ligand
BDBM74459
Substrate
n/a
Meas. Tech.
Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2
IC50
>79400±0 nM
Citation
 PubChem, PC Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2 PubChem Bioassay (2010)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 7
Synonyms:
He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:
Protein
Mol. Mass.:
40530.79
Organism:
Homo sapiens (Human)
Description:
P35236
Residue:
360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
  
Inhibitor
Name:
BDBM74459
Synonyms:
2-cycloheptyl-3-keto-3-(tetrahydrofurfurylamino)propionic acid methyl ester | 2-cycloheptyl-3-oxo-3-(2-oxolanylmethylamino)propanoic acid methyl ester | MLS000096812 | SMR000074495 | cid_3246767 | methyl 2-cycloheptyl-3-oxidanylidene-3-(oxolan-2-ylmethylamino)propanoate | methyl 2-cycloheptyl-3-oxo-3-(oxolan-2-ylmethylamino)propanoate | methyl 2-cycloheptyl-3-oxo-3-[(tetrahydro-2-furanylmethyl)amino]propanoate
Type:
Small organic molecule
Emp. Form.:
C16H27NO4
Mol. Mass.:
297.3899
SMILES:
COC(=O)C(C1CCCCCC1)C(=O)NCC1CCCO1
Structure:
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