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Target
Tyrosine-protein phosphatase non-receptor type 7
Ligand
BDBM74467
Substrate
n/a
Meas. Tech.
Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2
IC50
>79400±0 nM
Citation
 PubChem, PC Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2 PubChem Bioassay (2010)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 7
Synonyms:
He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:
Protein
Mol. Mass.:
40530.79
Organism:
Homo sapiens (Human)
Description:
P35236
Residue:
360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
  
Inhibitor
Name:
BDBM74467
Synonyms:
MLS000101596 | N-[2-(2-keto-7,8-dimethyl-1H-quinolin-3-yl)ethyl]butyramide | N-[2-(7,8-dimethyl-2-oxidanylidene-1H-quinolin-3-yl)ethyl]butanamide | N-[2-(7,8-dimethyl-2-oxo-1H-quinolin-3-yl)ethyl]butanamide | SMR000016207 | cid_3567340
Type:
Small organic molecule
Emp. Form.:
C17H22N2O2
Mol. Mass.:
286.3688
SMILES:
CCCC(=O)NCCc1cc2ccc(C)c(C)c2[nH]c1=O
Structure:
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