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Target
Tyrosine-protein phosphatase non-receptor type 7
Ligand
BDBM74471
Substrate
n/a
Meas. Tech.
Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2
IC50
>79400±0 nM
Citation
 PubChem, PC Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2 PubChem Bioassay (2010)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 7
Synonyms:
He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:
Protein
Mol. Mass.:
40530.79
Organism:
Homo sapiens (Human)
Description:
P35236
Residue:
360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
  
Inhibitor
Name:
BDBM74471
Synonyms:
4-(Naphthalene-2-sulfonyl)-piperazine-1-sulfonic acid dimethylamide | MLS000067221 | N,N-dimethyl-4-(2-naphthalenylsulfonyl)-1-piperazinesulfonamide | N,N-dimethyl-4-(2-naphthylsulfonyl)piperazine-1-sulfonamide | N,N-dimethyl-4-naphthalen-2-ylsulfonyl-piperazine-1-sulfonamide | N,N-dimethyl-4-naphthalen-2-ylsulfonylpiperazine-1-sulfonamide | SMR000124637 | cid_1094974
Type:
Small organic molecule
Emp. Form.:
C16H21N3O4S2
Mol. Mass.:
383.486
SMILES:
CN(C)S(=O)(=O)N1CCN(CC1)S(=O)(=O)c1ccc2ccccc2c1
Structure:
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