Reaction Details Report a problem with these data
Target
Tyrosine-protein phosphatase non-receptor type 22
Ligand
BDBM75329
Substrate
n/a
Meas. Tech.
SAR LYP1 Fluorescent Assay using pCAP substrate for In Vitro dose response studies - Set 3
IC50
>100000±n/a nM
Citation
 PubChem, PC SAR LYP1 Fluorescent Assay using pCAP substrate for In Vitro dose response studies - Set 3 PubChem Bioassay (2010)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 22
Synonyms:
3.1.3.48 | Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP | LyP | Lymphoid phosphatase | Lymphoid phosphatase (Lyp) | PEP | PEST-domain phosphatase | PTN22_HUMAN | PTPN22 | PTPN8 | Tyrosine-protein phosphatase non-receptor type 22 (LYP) | tyrosine-protein phosphatase non-receptor type 22 isoform 1
Type:
n/a
Mol. Mass.:
91712.31
Organism:
Homo sapiens (Human)
Description:
Q9Y2R2
Residue:
807
Sequence:
MDQREILQKFLDEAQSKKITKEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKKNRYKDILPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDFWRMIWEYSVLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPFSVSCEAEKRKSDYIIRTLKVKFNSETRTIYQFHYKNWPDHDVPSSIDPILELIWDVRCYQEDDSVPICIHCSAGCGRTGVICAIDYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQYELVYNAVLELFKRQMDVIRDKHSGTESQAKHCIPEKNHTLQADSYSPNLPKSTTKAAKMMNQQRTKMEIKESSSFDFRTSEISAKEELVLHPAKSSTSFDFLELNYSFDKNADTTMKWQTKAFPIVGEPLQKHQSLDLGSLLFEGCSNSKPVNAAGRYFNSKVPITRTKSTPFELIQQRETKEVDSKENFSYLESQPHDSCFVEMQAQKVMHVSSAELNYSLPYDSKHQIRNASNVKHHDSSALGVYSYIPLVENPYFSSWPPSGTSSKMSLDLPEKQDGTVFPSSLLPTSSTSLFSYYNSHDSLSLNSPTNISSLLNQESAVLATAPRIDDEIPPPLPVRTPESFIVVEEAGEFSPNVPKSLSSAVKVKIGTSLEWGGTSEPKKFDDSVILRPSKSVKLRSPKSELHQDRSSPPPPLPERTLESFFLADEDCMQAQSIETYSTSYPDTMENSTSSKQTLKTPGKSFTRSKSLKILRNMKKSICNSCPPNKPAESVQSNNSSSFLNFGFANRFSKPKGPRNPPPTWNI
  
Inhibitor
Name:
BDBM75329
Synonyms:
2-[4-[(Z)-[2-(4-hydroxy-N-methyl-anilino)-4-keto-2-thiazolin-5-ylidene]methyl]-2-methoxy-phenoxy]acetic acid | 2-[4-[(Z)-[2-(4-hydroxy-N-methylanilino)-4-oxo-1,3-thiazol-5-ylidene]methyl]-2-methoxyphenoxy]acetic acid | 2-[4-[(Z)-[2-(4-hydroxy-N-methylanilino)-4-oxo-5-thiazolylidene]methyl]-2-methoxyphenoxy]acetic acid | 2-[4-[(Z)-[2-[(4-hydroxyphenyl)-methyl-amino]-4-oxidanylidene-1,3-thiazol-5-ylidene]methyl]-2-methoxy-phenoxy]ethanoic acid | MLS-0146324.0001 | cid_2136948
Type:
Small organic molecule
Emp. Form.:
C20H18N2O6S
Mol. Mass.:
414.432
SMILES:
COc1cc(\C=C2/SC(=NC2=O)N(C)c2ccc(O)cc2)ccc1OCC(O)=O |c:8|
Structure:
Search PDB for entries with ligand similarity: