Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 3
Ligand
BDBM75364
Substrate
n/a
Meas. Tech.
SAR analysis of compounds that inhibit VHR1, Fluorescent Assay - Set 2
IC50
>100000±n/a nM
Citation
 PubChem, PC SAR analysis of compounds that inhibit VHR1, Fluorescent Assay - Set 2 PubChem Bioassay (2010)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM75364
Synonyms:
4-(phenylmethyl)-N-(4-sulfamoylphenyl)-1-piperazinecarboxamide | 4-(phenylmethyl)-N-(4-sulfamoylphenyl)piperazine-1-carboxamide | 4-benzyl-N-(4-sulfamoylphenyl)piperazine-1-carboxamide | MLS-0435629.0001 | cid_27869236
Type:
Small organic molecule
Emp. Form.:
C18H22N4O3S
Mol. Mass.:
374.457
SMILES:
NS(=O)(=O)c1ccc(NC(=O)N2CCN(Cc3ccccc3)CC2)cc1
Structure:
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