Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 3
Ligand
BDBM46210
Substrate
n/a
Meas. Tech.
SAR analysis of compounds that inhibit VHR1, Fluorescent Assay - Set 2
IC50
>100000±n/a nM
Citation
 PubChem, PC SAR analysis of compounds that inhibit VHR1, Fluorescent Assay - Set 2 PubChem Bioassay (2010)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM46210
Synonyms:
4-(1,3-benzodioxol-5-ylmethyl)-N-(4-sulfamoylphenyl)-1-piperazinecarbothioamide | 4-(1,3-benzodioxol-5-ylmethyl)-N-(4-sulfamoylphenyl)piperazine-1-carbothioamide | 4-piperonyl-N-(4-sulfamoylphenyl)piperazine-1-carbothioamide | MLS-0271926.0001 | cid_1213466
Type:
Small organic molecule
Emp. Form.:
C19H22N4O4S2
Mol. Mass.:
434.532
SMILES:
NS(=O)(=O)c1ccc(NC(=S)N2CCN(Cc3ccc4OCOc4c3)CC2)cc1
Structure:
Search PDB for entries with ligand similarity: