Reaction Details Report a problem with these data
Target
Glutathione S-transferase omega-1
Ligand
BDBM63200
Substrate
n/a
Meas. Tech.
Late stage assay provider results from the probe development effort to identify inhibitors of GSTO1: Gel-based activity-based protein profiling (ABPP) IC50
IC50
32±n/a nM
Citation
 PubChem, PC Late stage assay provider results from the probe development effort to identify inhibitors of GSTO1: Gel-based activity-based protein profiling (ABPP) IC50 PubChem Bioassay (2010)[AID] 
Target
Name:
Glutathione S-transferase omega-1
Synonyms:
GSTO 1-1 | GSTO1 | GSTO1_HUMAN | GSTTLP28 | Glutathione S-transferase omega-1 | Glutathione transferase omega 1 | glutathione S-transferase omega-1 isoform 1
Type:
PROTEIN
Mol. Mass.:
27565.54
Organism:
Homo sapiens (Human)
Description:
EBI_11172
Residue:
241
Sequence:
MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDYGL
  
Inhibitor
Name:
BDBM63200
Synonyms:
2-(3-chloro-N-(2-chloro-1-oxoethyl)anilino)-N-cyclohexyl-2-(4-methoxyphenyl)acetamide | 2-(3-chloro-N-(2-chloroacetyl)anilino)-N-cyclohexyl-2-(4-methoxyphenyl)acetamide | 2-[(chloroacetyl)(3-chlorophenyl)amino]-N-cyclohexyl-2-(4-methoxyphenyl)acetamide | 2-[2-chloranylethanoyl-(3-chlorophenyl)amino]-N-cyclohexyl-2-(4-methoxyphenyl)ethanamide | MLS000583963 | SMR000206949 | cid_12004949
Type:
Small organic molecule
Emp. Form.:
C23H26Cl2N2O3
Mol. Mass.:
449.37
SMILES:
COc1ccc(cc1)C(N(C(=O)CCl)c1cccc(Cl)c1)C(=O)NC1CCCCC1
Structure:
Search PDB for entries with ligand similarity: