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Target
Neuropeptides B/W receptor type 1
Ligand
BDBM75950
Substrate
n/a
Meas. Tech.
Late-stage fluorescence-based dose response cell-based screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7)
IC50
5400±n/a nM
Citation
 PubChem, PC Late-stage fluorescence-based dose response cell-based screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7) PubChem Bioassay (2010)[AID] 
Target
Name:
Neuropeptides B/W receptor type 1
Synonyms:
GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36111.82
Organism:
Homo sapiens (Human)
Description:
gi_119607128
Residue:
328
Sequence:
MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
  
Inhibitor
Name:
BDBM75950
Synonyms:
4,5-bis(chloranyl)-6-methoxy-2-(3-methylphenyl)pyridazin-3-one | 4,5-dichloro-6-methoxy-2-(3-methylphenyl)-3-pyridazinone | 4,5-dichloro-6-methoxy-2-(3-methylphenyl)pyridazin-3-one | 4,5-dichloro-6-methoxy-2-(m-tolyl)pyridazin-3-one | SR-02000000486 | SR-02000000486-1 | cid_24997711
Type:
Small organic molecule
Emp. Form.:
C12H10Cl2N2O2
Mol. Mass.:
285.126
SMILES:
COc1nn(-c2cccc(C)c2)c(=O)c(Cl)c1Cl
Structure:
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