Reaction Details Report a problem with these data
Target
Ammonium transporter MEP2
Ligand
BDBM76252
Substrate
n/a
Meas. Tech.
Confirmatory Cherry Pick 3 SAR Dose Response Multiplex in TOR pathway GFP-fusion proteins for Saccharomyes cerevisiae, specifically MEP2
EC50
74380±n/a nM
Citation
 PubChem, PC Confirmatory Cherry Pick 3 SAR Dose Response Multiplex in TOR pathway GFP-fusion proteins for Saccharomyes cerevisiae, specifically MEP2 PubChem Bioassay (2011)[AID] 
Target
Name:
Ammonium transporter MEP2
Synonyms:
AMT2 | MEP2 | MEP2_YEAST
Type:
Enzyme Catalytic Domain
Mol. Mass.:
53401.07
Organism:
Saccharomyces cerevisiae
Description:
gi_1302091
Residue:
499
Sequence:
MSYNFTGTPTGEGTGGNSLTTDLNTQFDLANMGWIGVASAGVWIMVPGIGLLYSGLSRKKHALSLLWASMMASAVCIFQWFFWGYSLAFSHNTRGNGFIGTLEFFGFRNVLGAPSSVSSLPDILFAVYQGMFAAVTGALMLGGACERARLFPMMVFLFLWMTIVYCPIACWVWNAEGWLVKLGSLDYAGGLCVHLTSGHGGLVYALILGKRNDPVTRKGMPKYKPHSVTSVVLGTVFLWFGWMFFNGGSAGNATIRAWYSIMSTNLAAACGGLTWMVIDYFRCGRKWTTVGLCSGIIAGLVGITPAAGFVPIWSAVVIGVVTGAGCNLAVDLKSLLRIDDGLDCYSIHGVGGCIGSVLTGIFAADYVNATAGSYISPIDGGWINHHYKQVGYQLAGICAALAWTVTVTSILLLTMNAIPFLKLRLSADEEELGTDAAQIGEFTYEESTAYIPEPIRSKTSAQMPPPHENIDDKIVGNTDAEKNSTPSDASSTKNTDHIV
  
Inhibitor
Name:
BDBM76252
Synonyms:
(6-amino-5-nitro-pyrimidin-4-yl)-(3,5-dichlorophenyl)amine | 4-N-(3,5-dichlorophenyl)-5-nitropyrimidine-4,6-diamine | MLS000581561 | N-(3,5-dichlorophenyl)-5-nitro-4,6-pyrimidinediamine | N4-(3,5-dichlorophenyl)-5-nitropyrimidine-4,6-diamine | N4-[3,5-bis(chloranyl)phenyl]-5-nitro-pyrimidine-4,6-diamine | SMR000200189 | cid_2959050
Type:
Small organic molecule
Emp. Form.:
C10H7Cl2N5O2
Mol. Mass.:
300.101
SMILES:
Nc1ncnc(Nc2cc(Cl)cc(Cl)c2)c1[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: