Reaction Details Report a problem with these data
Target
Delta-type opioid receptor
Ligand
BDBM71585
Substrate
n/a
Meas. Tech.
SAR Analysis of Antagonists of the DOR Receptor using an Image-Based Assay - Set 3
IC50
>32000±n/a nM
Citation
 PubChem, PC SAR Analysis of Antagonists of the DOR Receptor using an Image-Based Assay - Set 3 PubChem Bioassay (2010)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM71585
Synonyms:
KSC-5-281C | KUC104166N | N-[2-[(4-bromobenzyl)-isopropyl-amino]ethyl]-4-[[(4-methoxyphenyl)sulfonylamino]methyl]benzamide | N-[2-[(4-bromophenyl)methyl-propan-2-yl-amino]ethyl]-4-[[(4-methoxyphenyl)sulfonylamino]methyl]benzamide | N-[2-[(4-bromophenyl)methyl-propan-2-ylamino]ethyl]-4-[[(4-methoxyphenyl)sulfonylamino]methyl]benzamide | cid_44620903
Type:
Small organic molecule
Emp. Form.:
C27H32BrN3O4S
Mol. Mass.:
574.53
SMILES:
COc1ccc(cc1)S(=O)(=O)NCc1ccc(cc1)C(=O)NCCN(Cc1ccc(Br)cc1)C(C)C
Structure:
Search PDB for entries with ligand similarity: