Reaction Details Report a problem with these data
Target
Mu-type opioid receptor
Ligand
BDBM71589
Substrate
n/a
Meas. Tech.
SAR Analysis of Antagonists of the MOR Receptor using an Image-Based Assay - Set 3
IC50
>32000±n/a nM
Citation
 PubChem, PC SAR Analysis of Antagonists of the MOR Receptor using an Image-Based Assay - Set 3 PubChem Bioassay (2010)[AID] 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM71589
Synonyms:
KSC-11-40-1 | KUC104170N | N-[2-[(4-methoxyphenyl)methyl-propan-2-yl-amino]ethyl]-4-[[(4-methylphenyl)sulfonylamino]methyl]benzamide | N-[2-[(4-methoxyphenyl)methyl-propan-2-ylamino]ethyl]-4-[[(4-methylphenyl)sulfonylamino]methyl]benzamide | N-[2-[isopropyl(p-anisyl)amino]ethyl]-4-[(tosylamino)methyl]benzamide | cid_44620909
Type:
Small organic molecule
Emp. Form.:
C28H35N3O4S
Mol. Mass.:
509.66
SMILES:
COc1ccc(CN(CCNC(=O)c2ccc(CNS(=O)(=O)c3ccc(C)cc3)cc2)C(C)C)cc1
Structure:
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