Reaction Details Report a problem with these data
Target
Alkaline phosphatase, germ cell type
Ligand
BDBM60497
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS inhibitors of Mouse Intestinal Alkaline Phosphatase using Placental Alkaline Phosphatase
IC50
18000±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS inhibitors of Mouse Intestinal Alkaline Phosphatase using Placental Alkaline Phosphatase PubChem Bioassay (2010)[AID] 
Target
Name:
Alkaline phosphatase, germ cell type
Synonyms:
ALPG | ALPPL | ALPPL2 | Alkaline phosphatase placental-like | PPBN_HUMAN | placental-like alkaline phosphatase preproprotein
Type:
PROTEIN
Mol. Mass.:
57374.31
Organism:
Homo sapiens (Human)
Description:
ChEMBL_29964
Residue:
532
Sequence:
MQGPWVLLLLGLRLQLSLGIIPVEEENPDFWNRQAAEALGAAKKLQPAQTAAKNLIIFLGDGMGVSTVTAARILKGQKKDKLGPETFLAMDRFPYVALSKTYSVDKHVPDSGATATAYLCGVKGNFQTIGLSAAARFNQCNTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGAYAHTVNRNWYSDADVPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPDDYSQGGTRLDGKNLVQEWLAKHQGARYVWNRTELLQASLDPSVTHLMGLFEPGDMKYEIHRDSTLDPSLMEMTEAALLLLSRNPRGFFLFVEGGRIDHGHHESRAYRALTETIMFDDAIERAGQLTSEEDTLSLVTADHSHVFSFGGYPLRGSSIFGLAPGKARDRKAYTVLLYGNGPGYVLKDGARPDVTESESGSPEYRQQSAVPLDGETHAGEDVAVFARGPQAHLVHGVQEQTFIAHVMAFAACLEPYTACDLAPRAGTTDAAHPGPSVVPALLPLLAGTLLLLGTATAP
  
Inhibitor
Name:
BDBM60497
Synonyms:
4-Methyl-furazan-3-carboxylic acid (3,4-dihydroxy-benzylidene)-hydrazide | MLS000554508 | N-[(3,4-diketocyclohexa-1,5-dien-1-yl)methyleneamino]-4-methyl-2,5-dihydrofurazan-3-carboxamide | N-[(3,4-dioxo-1-cyclohexa-1,5-dienyl)methylideneamino]-4-methyl-2,5-dihydro-1,2,5-oxadiazole-3-carboxamide | N-[(3,4-dioxocyclohexa-1,5-dien-1-yl)methylideneamino]-4-methyl-2,5-dihydro-1,2,5-oxadiazole-3-carboxamide | N-[[3,4-bis(oxidanylidene)cyclohexa-1,5-dien-1-yl]methylideneamino]-4-methyl-2,5-dihydro-1,2,5-oxadiazole-3-carboxamide | SMR000171281 | cid_6744580
Type:
Small organic molecule
Emp. Form.:
C11H10N4O4
Mol. Mass.:
262.2215
SMILES:
CC1NON=C1C(=O)NN=CC1=CC(=O)C(=O)C=C1 |w:9.9,c:4,18,t:12|
Structure:
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