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Target
Sentrin-specific protease 8
Ligand
BDBM76369
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay
IC50
1560±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay PubChem Bioassay (2010)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM76369
Synonyms:
MLS000100578 | N-(1,3-benzothiazol-2-yl)-5-chloranyl-thiophene-2-carboxamide | N-(1,3-benzothiazol-2-yl)-5-chloro-2-thiophenecarboxamide | N-(1,3-benzothiazol-2-yl)-5-chloro-thiophene-2-carboxamide | N-(1,3-benzothiazol-2-yl)-5-chlorothiophene-2-carboxamide | SMR000017422 | cid_2414873
Type:
Small organic molecule
Emp. Form.:
C12H7ClN2OS2
Mol. Mass.:
294.78
SMILES:
Clc1ccc(s1)C(=O)Nc1nc2ccccc2s1
Structure:
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