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Target
Sentrin-specific protease 8
Ligand
BDBM76488
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay
IC50
2430±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay PubChem Bioassay (2010)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM76488
Synonyms:
(1-pyridin-2-ylethylideneamino) 4-bromanylbenzoate | (1-pyridin-2-ylethylideneamino) 4-bromobenzoate | 1-(2-pyridinyl)ethanone O-(4-bromobenzoyl)oxime | 4-bromobenzoic acid [1-(2-pyridinyl)ethylideneamino] ester | 4-bromobenzoic acid [1-(2-pyridyl)ethylideneamino] ester | MLS000681107 | SMR000269364 | cid_770951
Type:
Small organic molecule
Emp. Form.:
C14H11BrN2O2
Mol. Mass.:
319.153
SMILES:
CC(=NOC(=O)c1ccc(Br)cc1)c1ccccn1
Structure:
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