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Target
Sentrin-specific protease 8
Ligand
BDBM76569
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay
IC50
1830±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay PubChem Bioassay (2010)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM76569
Synonyms:
(3Z)-1-ethyl-3-(2-quinolinylhydrazinylidene)-2-indolone | (3Z)-1-ethyl-3-(2-quinolylhydrazono)oxindole | (3Z)-1-ethyl-3-(quinolin-2-ylhydrazinylidene)indol-2-one | 1-Ethyl-3-(quinolin-2-yl-hydrazono)-1,3-dihydro-indol-2-one | MLS000778542 | SMR000415336 | cid_6040562
Type:
Small organic molecule
Emp. Form.:
C19H16N4O
Mol. Mass.:
316.3565
SMILES:
CCN1C(=O)C(=NNc2ccc3ccccc3n2)c2ccccc12 |w:6.6|
Structure:
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