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Target
Sentrin-specific protease 8
Ligand
BDBM46593
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay
IC50
4780±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay PubChem Bioassay (2010)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM46593
Synonyms:
2,6-bis(chloranyl)-N-[2-oxidanyl-1,3-bis(oxidanylidene)inden-2-yl]benzamide | 2,6-dichloro-N-(2-hydroxy-1,3-diketo-indan-2-yl)benzamide | 2,6-dichloro-N-(2-hydroxy-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)benzamide | 2,6-dichloro-N-(2-hydroxy-1,3-dioxo-2-indenyl)benzamide | 2,6-dichloro-N-(2-hydroxy-1,3-dioxoinden-2-yl)benzamide | MLS000830225 | SMR000458146 | cid_2810445
Type:
Small organic molecule
Emp. Form.:
C16H9Cl2NO4
Mol. Mass.:
350.153
SMILES:
OC1(NC(=O)c2c(Cl)cccc2Cl)C(=O)c2ccccc2C1=O
Structure:
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