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Target
Sentrin-specific protease 8
Ligand
BDBM64802
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay
IC50
2470±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay PubChem Bioassay (2010)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM64802
Synonyms:
(6,7-dimethoxy-1-isoquinolinyl)-(3,4-dimethoxyphenyl)methanone | (6,7-dimethoxy-1-isoquinolyl)-(3,4-dimethoxyphenyl)methanone | (6,7-dimethoxyisoquinolin-1-yl)-(3,4-dimethoxyphenyl)methanone | MLS001360484 | SMR001223913 | cid_96932
Type:
Small organic molecule
Emp. Form.:
C20H19NO5
Mol. Mass.:
353.3686
SMILES:
COc1ccc(cc1OC)C(=O)c1nccc2cc(OC)c(OC)cc12
Structure:
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