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Target
Caspase-3
Ligand
BDBM77501
Substrate
n/a
Meas. Tech.
Absorbance-based biochemical high throughput dose response assay for activators of procaspase-3
EC50
419.96±n/a nM
Citation
 PubChem, PC Absorbance-based biochemical high throughput dose response assay for activators of procaspase-3 PubChem Bioassay (2010)[AID] 
Target
Name:
Caspase-3
Synonyms:
Apopain | CASP-3 | CASP3 | CASP3_HUMAN | CPP-32 | CPP32 | Caspase 3 | Caspase-3 subunit p12 | Caspase-3 subunit p17 | Cysteine protease CPP32 | SCA-1 | SREBP cleavage activity 1 | Yama protein | caspase-3 preproprotein
Type:
Hydrolase; heterotetramer of two heterodimers
Mol. Mass.:
31607.55
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
277
Sequence:
MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH
  
Inhibitor
Name:
BDBM77501
Synonyms:
(5E)-2-(4-methoxyphenyl)-5-(3,4,5-trimethoxybenzylidene)-1,3-oxazol-4(5H)-one | (5E)-2-(4-methoxyphenyl)-5-(3,4,5-trimethoxybenzylidene)-2-oxazolin-4-one | (5E)-2-(4-methoxyphenyl)-5-[(3,4,5-trimethoxyphenyl)methylidene]-1,3-oxazol-4-one | (5E)-2-(4-methoxyphenyl)-5-[(3,4,5-trimethoxyphenyl)methylidene]-4-oxazolone | MLS000585672 | SMR000204235 | cid_12005122
Type:
Small organic molecule
Emp. Form.:
C20H19NO6
Mol. Mass.:
369.368
SMILES:
COc1ccc(cc1)C1=NC(=O)\C(O1)=C/c1cc(OC)c(OC)c(OC)c1 |t:9|
Structure:
Search PDB for entries with ligand similarity: