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Target
Ubiquitin-conjugating enzyme E2 N
Ligand
BDBM78521
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay
IC50
1534±76 nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay PubChem Bioassay (2011)[AID] 
Target
Name:
Ubiquitin-conjugating enzyme E2 N
Synonyms:
BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N
Type:
PROTEIN
Mol. Mass.:
17137.61
Organism:
Homo sapiens (Human)
Description:
EBI_101440
Residue:
152
Sequence:
MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI
  
Inhibitor
Name:
BDBM78521
Synonyms:
2-[4-(5-Fluoro-2-methyl-benzoimidazol-1-yl)-piperidin-1-yl]-N-(2-methoxy-phenyl)-acetamide | 2-[4-(5-fluoranyl-2-methyl-benzimidazol-1-yl)piperidin-1-yl]-N-(2-methoxyphenyl)ethanamide | 2-[4-(5-fluoro-2-methyl-1-benzimidazolyl)-1-piperidinyl]-N-(2-methoxyphenyl)acetamide | 2-[4-(5-fluoro-2-methyl-benzimidazol-1-yl)piperidino]-N-(2-methoxyphenyl)acetamide | 2-[4-(5-fluoro-2-methylbenzimidazol-1-yl)piperidin-1-yl]-N-(2-methoxyphenyl)acetamide | MLS000074439 | SMR000006465 | cid_649329
Type:
Small organic molecule
Emp. Form.:
C22H25FN4O2
Mol. Mass.:
396.4579
SMILES:
COc1ccccc1NC(=O)CN1CCC(CC1)n1c(C)nc2cc(F)ccc12
Structure:
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