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Target
Ubiquitin-conjugating enzyme E2 N
Ligand
BDBM79333
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay
IC50
3607±161 nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay PubChem Bioassay (2011)[AID] 
Target
Name:
Ubiquitin-conjugating enzyme E2 N
Synonyms:
BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N
Type:
PROTEIN
Mol. Mass.:
17137.61
Organism:
Homo sapiens (Human)
Description:
EBI_101440
Residue:
152
Sequence:
MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI
  
Inhibitor
Name:
BDBM79333
Synonyms:
MLS002391554 | SMR001355522 | [4-(8-hydroxy-6-quinolinyl)phenyl]-(1-piperazinyl)methanone;2,2,2-trifluoroacetic acid | [4-(8-hydroxy-6-quinolyl)phenyl]-piperazino-methanone;2,2,2-trifluoroacetic acid | [4-(8-hydroxyquinolin-6-yl)phenyl]-piperazin-1-ylmethanone;2,2,2-trifluoroacetic acid | [4-(8-oxidanylquinolin-6-yl)phenyl]-piperazin-1-yl-methanone;2,2,2-tris(fluoranyl)ethanoic acid | cid_44143204
Type:
Small organic molecule
Emp. Form.:
C20H19N3O2
Mol. Mass.:
333.3838
SMILES:
Oc1cc(cc2cccnc12)-c1ccc(cc1)C(=O)N1CCNCC1
Structure:
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