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Target
Ubiquitin-conjugating enzyme E2 N
Ligand
BDBM79118
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm
IC50
2140±58 nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm PubChem Bioassay (2011)[AID] 
Target
Name:
Ubiquitin-conjugating enzyme E2 N
Synonyms:
BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N
Type:
PROTEIN
Mol. Mass.:
17137.61
Organism:
Homo sapiens (Human)
Description:
EBI_101440
Residue:
152
Sequence:
MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI
  
Inhibitor
Name:
BDBM79118
Synonyms:
MLS001158319 | N'-(3-aminocarbonyl-5,5-dimethyl-4,7-dihydrothieno[2,3-c]pyran-2-yl)-N-(3-morpholin-4-ylpropyl)ethanediamide | N'-(3-carbamoyl-5,5-dimethyl-4,7-dihydrothieno[2,3-c]pyran-2-yl)-N-(3-morpholin-4-ylpropyl)oxamide | N'-(3-carbamoyl-5,5-dimethyl-4,7-dihydrothieno[2,3-c]pyran-2-yl)-N-(3-morpholinopropyl)oxamide | N'-(3-carbamoyl-5,5-dimethyl-4,7-dihydrothieno[2,3-c]pyran-2-yl)-N-[3-(4-morpholinyl)propyl]oxamide | SMR000652143 | cid_17583803
Type:
Small organic molecule
Emp. Form.:
C19H28N4O5S
Mol. Mass.:
424.514
SMILES:
CC1(C)Cc2c(CO1)sc(NC(=O)C(=O)NCCCN1CCOCC1)c2C(N)=O
Structure:
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