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Target
Perilipin-5
Ligand
BDBM79406
Substrate
n/a
Meas. Tech.
Luminescence-based biochemical high throughput dose response assay for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain
IC50
6970±n/a nM
Citation
 PubChem, PC Luminescence-based biochemical high throughput dose response assay for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5) (2K validation set) PubChem Bioassay (2011)[AID] 
Target
Name:
Perilipin-5
Synonyms:
LSDP5 | OXPAT | PAT-1 | PLIN5 | PLIN5_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50774.20
Organism:
Homo sapiens (Human)
Description:
gi_116292172
Residue:
463
Sequence:
MSEEEAAQIPRSSVWEQDQQNVVQRVVALPLVRATCTAVCDVYSAAKDRHPLLGSACRLAENCVCGLTTRALDHAQPLLEHLQPQLATMNSLACRGLDKLEEKLPFLQQPSETVVTSAKDVVASSVTGVVDLARRGRRWSVELKRSVSHAVDVVLEKSEELVDHFLPMTEEELAALAAEAEGPEVGSVEDQRRQQGYFVRLGSLSARIRHLAYEHSVGKLRQSKHRAQDTLAQLQETLELIDHMQCGVTPTAPACPGKVHELWGEWGQRPPESRRRSQAELETLVLSRSLTQELQGTVEALESSVRGLPAGAQEKVAEVRRSVDALQTAFADARCFRDVPAAALAEGRGRVAHAHACVDELLELVVQAVPLPWLVGPFAPILVERPEPLPDLADLVDEVIGGPDPRWAHLDWPAQQRAWEAEHRDGSGNGDGDRMGVAGDICEQEPETPSCPVKHTLMPELDF
  
Inhibitor
Name:
BDBM79406
Synonyms:
2-(6-methoxy-3',3'-dimethyl-1'-spiro[1-benzopyran-2,2'-indole]yl)ethanol | 2-(6-methoxy-3',3'-dimethyl-spiro[chromene-2,2'-indole]-1'-yl)ethanol | 2-(6-methoxy-3',3'-dimethyl-spiro[chromene-2,2'-indoline]-1'-yl)ethanol | 2-(6-methoxy-3',3'-dimethylspiro[chromene-2,2'-indole]-1'-yl)ethanol | MLS000080939 | SMR000047678 | cid_666429
Type:
Small organic molecule
Emp. Form.:
C21H23NO3
Mol. Mass.:
337.4122
SMILES:
COc1ccc2OC3(C=Cc2c1)N(CCO)c1ccccc1C3(C)C |c:8|
Structure:
Search PDB for entries with ligand similarity: