Reaction Details Report a problem with these data
Target
Neurotensin receptor type 1
Ligand
BDBM50895
Substrate
n/a
Meas. Tech.
Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1
EC50
7500±n/a nM
Citation
 PubChem, PC Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1 PubChem Bioassay (2011)[AID] 
Target
Name:
Neurotensin receptor type 1
Synonyms:
Dopamine receptor D2L/neurotensin receptor NTS1 | NTR1_HUMAN | NTRR | NTSR1 | Neurotensin receptor 1 | neurotensin receptor type 1
Type:
PROTEIN
Mol. Mass.:
46278.89
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1453811
Residue:
418
Sequence:
MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY
  
Inhibitor
Name:
BDBM50895
Synonyms:
(4Z)-4-[[5-(2,5-dichlorophenyl)-2-furanyl]methylidene]-3-methyl-5-isoxazolone | (4Z)-4-[[5-(2,5-dichlorophenyl)-2-furyl]methylene]-3-methyl-2-isoxazolin-5-one | (4Z)-4-[[5-(2,5-dichlorophenyl)furan-2-yl]methylidene]-3-methyl-1,2-oxazol-5-one | (4Z)-4-[[5-[2,5-bis(chloranyl)phenyl]furan-2-yl]methylidene]-3-methyl-1,2-oxazol-5-one | 4-{[5-(2,5-dichlorophenyl)-2-furyl]methylene}-3-methyl-5(4H)-isoxazolone | MLS000534352 | SMR000141784 | cid_5733602
Type:
Small organic molecule
Emp. Form.:
C15H9Cl2NO3
Mol. Mass.:
322.143
SMILES:
CC1=NOC(=O)\C1=C/c1ccc(o1)-c1cc(Cl)ccc1Cl |t:1|
Structure:
Search PDB for entries with ligand similarity: