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Target
Neurotensin receptor type 1
Ligand
BDBM79551
Substrate
n/a
Meas. Tech.
Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1
EC50
12000±n/a nM
Citation
 PubChem, PC Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1 PubChem Bioassay (2011)[AID] 
Target
Name:
Neurotensin receptor type 1
Synonyms:
Dopamine receptor D2L/neurotensin receptor NTS1 | NTR1_HUMAN | NTRR | NTSR1 | Neurotensin receptor 1 | neurotensin receptor type 1
Type:
PROTEIN
Mol. Mass.:
46278.89
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1453811
Residue:
418
Sequence:
MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY
  
Inhibitor
Name:
BDBM79551
Synonyms:
2-fluorobenzoic acid [2-[(Z)-3-(2-benzofuranyl)-3-oxoprop-1-enyl]phenyl] ester | 2-fluorobenzoic acid [2-[(Z)-3-(benzofuran-2-yl)-3-keto-prop-1-enyl]phenyl] ester | MLS000389185 | SMR000255458 | [2-[(Z)-3-(1-benzofuran-2-yl)-3-oxidanylidene-prop-1-enyl]phenyl] 2-fluoranylbenzoate | [2-[(Z)-3-(1-benzofuran-2-yl)-3-oxoprop-1-enyl]phenyl] 2-fluorobenzoate | cid_15945158
Type:
Small organic molecule
Emp. Form.:
C24H15FO4
Mol. Mass.:
386.3719
SMILES:
Fc1ccccc1C(=O)Oc1ccccc1\C=C/C(=O)c1cc2ccccc2o1
Structure:
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