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Target
Neurotensin receptor type 1
Ligand
BDBM79553
Substrate
n/a
Meas. Tech.
Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1
EC50
>40000±n/a nM
Citation
 PubChem, PC Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1 PubChem Bioassay (2011)[AID] 
Target
Name:
Neurotensin receptor type 1
Synonyms:
Dopamine receptor D2L/neurotensin receptor NTS1 | NTR1_HUMAN | NTRR | NTSR1 | Neurotensin receptor 1 | neurotensin receptor type 1
Type:
PROTEIN
Mol. Mass.:
46278.89
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1453811
Residue:
418
Sequence:
MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY
  
Inhibitor
Name:
BDBM79553
Synonyms:
(E)-2-butenedioic acid bis[2-(1-adamantylamino)-2-oxoethyl] ester | (E)-but-2-enedioic acid bis[2-(1-adamantylamino)-2-keto-ethyl] ester | MLS000335649 | SMR000253403 | bis[2-(1-adamantylamino)-2-oxidanylidene-ethyl] (E)-but-2-enedioate | bis[2-(1-adamantylamino)-2-oxoethyl] (E)-but-2-enedioate | cid_6186682
Type:
Small organic molecule
Emp. Form.:
C28H38N2O6
Mol. Mass.:
498.6111
SMILES:
[H]C12CC3([H])CC([H])(C1)CC(C2)(C3)NC(=O)COC(=O)\C=C\C(=O)OCC(=O)NC12CC3([H])CC([H])(CC([H])(C3)C1)C2 |TLB:33:34:40:31.30.39,39:31:41:37.40.36,8:6:12:1.11.2,8:1:12:6.9.5,THB:33:31:40:34.41.36,2:1:9:3.12.5|
Structure:
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