Reaction Details Report a problem with these data
Target
Neurotensin receptor type 1
Ligand
BDBM79556
Substrate
n/a
Meas. Tech.
Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1
EC50
11100±n/a nM
Citation
 PubChem, PC Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1 PubChem Bioassay (2011)[AID] 
Target
Name:
Neurotensin receptor type 1
Synonyms:
Dopamine receptor D2L/neurotensin receptor NTS1 | NTR1_HUMAN | NTRR | NTSR1 | Neurotensin receptor 1 | neurotensin receptor type 1
Type:
PROTEIN
Mol. Mass.:
46278.89
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1453811
Residue:
418
Sequence:
MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY
  
Inhibitor
Name:
BDBM79556
Synonyms:
3-(4-fluorophenyl)-2-(4-fluorophenyl)imino-4-keto-1,3-thiazine-6-carboxylic acid methyl ester | 3-(4-fluorophenyl)-2-(4-fluorophenyl)imino-4-oxo-1,3-thiazine-6-carboxylic acid methyl ester | MLS000586864 | SMR000208794 | cid_1519056 | methyl (2Z)-3-(4-fluorophenyl)-2-[(4-fluorophenyl)imino]-4-oxo-3,4-dihydro-2H-1,3-thiazine-6-carboxylate | methyl 3-(4-fluorophenyl)-2-(4-fluorophenyl)imino-4-oxidanylidene-1,3-thiazine-6-carboxylate | methyl 3-(4-fluorophenyl)-2-(4-fluorophenyl)imino-4-oxo-1,3-thiazine-6-carboxylate
Type:
Small organic molecule
Emp. Form.:
C18H12F2N2O3S
Mol. Mass.:
374.361
SMILES:
COC(=O)c1cc(=O)n(-c2ccc(F)cc2)\c(=N\c2ccc(F)cc2)s1
Structure:
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