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Target
Tropomyosin alpha-1 chain
Ligand
BDBM79671
Substrate
n/a
Meas. Tech.
Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)
EC50
>71500±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay (2011)[AID] 
Target
Name:
Tropomyosin alpha-1 chain
Synonyms:
TPM1 | TPM1_PIG | cardiac alpha tropomyosin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
32681.01
Organism:
Sus scrofa
Description:
P42639
Residue:
284
Sequence:
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKYSEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
  
Inhibitor
Name:
BDBM79671
Synonyms:
(4Z)-4-[(3-chloroanilino)methylene]-5-(trifluoromethyl)-2-pyrazolin-3-one | (4Z)-4-[(3-chloroanilino)methylidene]-3-(trifluoromethyl)-1H-pyrazol-5-one | (4Z)-4-[[(3-chlorophenyl)amino]methylidene]-3-(trifluoromethyl)-1H-pyrazol-5-one | 4-[(3-chloroanilino)methylene]-5-(trifluoromethyl)-2,4-dihydro-3H-pyrazol-3-one | MLS000327868 | SMR000168427 | cid_5843062
Type:
Small organic molecule
Emp. Form.:
C11H7ClF3N3O
Mol. Mass.:
289.641
SMILES:
FC(F)(F)c1[nH][nH]c(=O)c1C=Nc1cccc(Cl)c1 |w:11.12|
Structure:
Search PDB for entries with ligand similarity: