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Target
Tropomyosin alpha-1 chain
Ligand
BDBM79680
Substrate
n/a
Meas. Tech.
Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)
EC50
5480±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay (2011)[AID] 
Target
Name:
Tropomyosin alpha-1 chain
Synonyms:
TPM1 | TPM1_PIG | cardiac alpha tropomyosin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
32681.01
Organism:
Sus scrofa
Description:
P42639
Residue:
284
Sequence:
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKYSEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
  
Inhibitor
Name:
BDBM79680
Synonyms:
(5Z)-1-(4-methylphenyl)-5-[(E)-3-phenylazanylprop-2-enylidene]-1,3-diazinane-2,4,6-trione | (5Z)-5-[(E)-3-anilinoprop-2-enylidene]-1-(4-methylphenyl)-1,3-diazinane-2,4,6-trione | (5Z)-5-[(E)-3-anilinoprop-2-enylidene]-1-(p-tolyl)barbituric acid | 5-[(E)-3-Phenylamino-prop-2-en-(Z)-ylidene]-1-p-tolyl-pyrimidine-2,4,6-trione | MLS000587900 | SMR000211917 | cid_6049677
Type:
Small organic molecule
Emp. Form.:
C20H17N3O3
Mol. Mass.:
347.3673
SMILES:
Cc1ccc(cc1)-n1c(O)c(C=CC=Nc2ccccc2)c(=O)[nH]c1=O |w:14.15,11.11|
Structure:
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