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Target
Tropomyosin alpha-1 chain
Ligand
BDBM51079
Substrate
n/a
Meas. Tech.
Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)
EC50
1465±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay (2011)[AID] 
Target
Name:
Tropomyosin alpha-1 chain
Synonyms:
TPM1 | TPM1_PIG | cardiac alpha tropomyosin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
32681.01
Organism:
Sus scrofa
Description:
P42639
Residue:
284
Sequence:
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKYSEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
  
Inhibitor
Name:
BDBM51079
Synonyms:
MLS000588145 | N-[(5Z)-4-keto-5-[(1-methylindol-3-yl)methylene]-2-thioxo-thiazolidin-3-yl]benzamide | N-[(5Z)-5-[(1-methyl-3-indolyl)methylidene]-4-oxo-2-sulfanylidene-3-thiazolidinyl]benzamide | N-[(5Z)-5-[(1-methylindol-3-yl)methylidene]-4-oxidanylidene-2-sulfanylidene-1,3-thiazolidin-3-yl]benzamide | N-[(5Z)-5-[(1-methylindol-3-yl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]benzamide | N-{5-[1-(1-Methyl-1H-indol-3-yl)-meth-(Z)-ylidene]-4-oxo-2-thioxo-thiazolidin-3-yl}-benzamide | SMR000220188 | cid_2009322
Type:
Small organic molecule
Emp. Form.:
C20H15N3O2S2
Mol. Mass.:
393.482
SMILES:
Cn1cc(\C=C2/SC(=S)N(NC(=O)c3ccccc3)C2=O)c2ccccc12
Structure:
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