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DNA dC->dU-editing enzyme APOBEC-3G
Ligand
BDBM46833
Substrate
n/a
Meas. Tech.
Dose Response confirmation of APOBEC3A DNA Deaminase Inhibitors via a A3G counterscreen
Temperature
298.15±n/a K
IC50
1890±118 nM
Comments
extracted
Citation
PubChem, PC Dose Response confirmation of APOBEC3A DNA Deaminase Inhibitors via a A3G counterscreen PubChem Bioassay (2011)[AID] More Info.:
Target
Name:
DNA dC->dU-editing enzyme APOBEC-3G
Synonyms:
ABC3G_HUMAN | APOBEC3G
Type:
Enzyme Catalytic Domain
Mol. Mass.:
46419.54
Organism:
Homo sapiens (Human)
Description:
gi_13399304
Residue:
384
Sequence:
MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYSELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFVARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFISKNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQPWDGLDEHSQDLSGRLRAILQNQEN
Inhibitor
Name:
BDBM46833
Synonyms:
(2Z)-2-(1,3-dioxolan-4-ylidene)-N,N,N-trimethylethanaminium | MLS000047708 | SMR000033717 | [(2Z)-2-(1,3-dioxolan-4-ylidene)ethyl]-trimethyl-ammonium;iodide | [(2Z)-2-(1,3-dioxolan-4-ylidene)ethyl]-trimethyl-azanium;iodide | [(2Z)-2-(1,3-dioxolan-4-ylidene)ethyl]-trimethylammonium;iodide | [(2Z)-2-(1,3-dioxolan-4-ylidene)ethyl]-trimethylazanium;iodide | cid_5771435
Type:
Small organic molecule
Emp. Form.:
C8H16NO2
Mol. Mass.:
158.2176
SMILES:
C[N+](C)(C)C\C=C1\COCO1
Structure:
